Open Access Original Research Article

Prevalence of Glucose-6-Phosphate Dehydrogenase Deficiency among the Ogoni and Etche Ethnic Groups in Rivers State, Nigeria

Eze, Evelyn Mgbeoma, Christian, Serekara Gideon, Okere, Thankgod Onuabuchi

Asian Journal of Medicine and Health, Page 1-6
DOI: 10.9734/AJMAH/2019/46616

Aims: This study was aimed at determining the prevalence of Glucose-6-phosphate dehydrogenase deficiency (G6PD) among Ogoni and Etche ethnic groups in Rivers State, Nigeria,

Study Design:  A total of 200 randomly selected subjects comprising of 100 Ogonis (49 males and 51 females) and 100 Etches (62 males and 38 females) participated in this study.

Place and Duration of Study: The study was conducted among members of Ogoni and Etche ethnic groups. Analysis was carried out at the Haematology Laboratory, Department of Medical Laboratory Science, Rivers State University, Port Harcourt, Nigeria, between May and August, 2018.

Methodology: Three milliliters of ethylene diamine tetra acetic acid (EDTA) anticoagulated blood was collected from each subject, The G6PD status of the subjects were determined by spectrophotometric method using semi-automated analyzer.

Results: The result obtained showed that the prevalence of G6PD deficiency in Ogoni was 9% while that of Etche was 13%. There was no significant difference (P=0.19) in the level of deficiency in both the Ogoni and Etche subjects with the value of 6.21±4.34 and 5.92±0.54 respectively.

Conclusion: G6PD is more common among Etches than the Ogonis, although with no significant difference. Therefore, G6PD screening test should be included in routine test before treatment with antimalarial drugs like quinine and premaquinine or other drugs that can predispose G6PD deficient individuals to haemolytic episode.

Open Access Original Research Article

Prevalence of Falls and Associated Factors among Construction Workers in Port Harcourt, Nigeria

F. A. Ngwu, I. D. Alabere, K. E. Douglas

Asian Journal of Medicine and Health, Page 1-16
DOI: 10.9734/AJMAH/2019/46662

Background: Falls at construction sites are common occurrences with some resulting in fatalities. This study was to determine the prevalence and pattern of falls at construction sites in Port Harcourt Metropolis, Nigeria.

Materials and Methods: This descriptive cross-sectional study sampled 340 construction workers from the two Local Government Areas of Port Harcourt Metropolis. A structured, close-ended, interviewer-administered questionnaire and Walk through Survey were the research instruments.  Ethical approval was gotten from the Research and Ethics Committee of University of Port Harcourt and informed consent was gotten from each of the respondents prior to commencement of the study. Data obtained were analysed using descriptive and analytical statistics.

Results: Of the 340 respondents in the study, 124 had experienced falls giving a prevalence of 36.5%. On the pattern of falls, trips/slips from short distance accounted for 23.4% while falls from ladder was 17.7%, scaffolds 15.3% and roof tops accounted for 12.9%. The commonest cause of the falls was failure to use Personal Protective Equipment PPE (17.7%). Furthermore, 63.2% of the respondents had good knowledge of safety precautions while 57.4% had good safety practice. Knowledge of safety precautions was significantly associated with age, education, experience and safety training (p = 0.000).

Conclusion: There was a high prevalence of falls at construction sites in Port Harcourt mainly from trips/slips, ladders and scaffolds. Majority of the workers had good knowledge and practice of safety precautions. It is recommended that health education, periodic safety training and enforcement of safety practices among construction workers be instituted, intensified and sustained.

Open Access Original Research Article

Gender Differences in the Effect of Diabetes Mellitus in Serum Lipid of Diabetics Attending Plateau State Specialist Hospital

Luka Carrol Domkat, Agi Peace Josephine, Egwuindu Josephine Chika, Istifanus Gurumtet, Comfort Japhet Philip

Asian Journal of Medicine and Health, Page 1-8
DOI: 10.9734/AJMAH/2019/45360

Background: Diabetes is an increasing health concern globally with several complications (including coronary heart disease) and diverse contributing factors. Diabetes has been proven to affect both male and females nevertheless, the attendant dyslipidemia is suspected to be common among females than males.

Objectives: This study is aimed at evaluating the effect of gender on the serum lipid profile of diabetics.

Methods: One hundred and eighty six (186) diabetics comprising 86 males and 100 female diabetics of all groups, attending plateau state specialist hospital Jos were admitted as subjects in this study. While 50 control samples were collected from apparently healthy non-diabetics. The BMI and Blood pressure of the subjects was determined on the site of sample collection, while the blood samples were analyzed in the laboratory using a fully automated biochemistry analyzer. The parameters assayed include; Total cholesterol, High density lipoproteins, Low density lipoproteins, Triglycerides and Fasting blood glucose. 

Results: Results generated revealed a significant (p = .05) variation in the total cholesterol, Low Density Lipoprotein and Blood pressure values of male and female diabetics while triglycerides values varied significantly (p = 0.05) between diabetics and controls subjects of both sexes accordingly. The results further revealed that female diabetics above 60 yrs had higher total cholesterol (5.5±1.5 mmol/L), Triglycerides (1.6±1.4 mmol/L), LDL (2.9±1.5 mmol/L) and Systolic blood pressure (15.58±2.19×10 mmHg) values, and the lowest HDL (1.9±0.3 mmol/L) value when compared to the values gotten from the other age groups. While those between the ages of 21-40 yrs had the lowest Total cholesterol (4.2±0.8 mmol/L), Triglycerides (1.3±0.9 mmol/L), LDL (1.5±1.0 mmol/L), BMI (25.2±5.7 Kg/m2) and Systolic blood pressure (13.4±2.29×10 mmHg) values.

Conclusion: This study unveils the possibility of the female diabetics being more prone to dyslipidemia than the male gender thus exposing the females to increased risk of coronary heart disease. Although, both males and females alike are exposed to the metabolic syndrome, the female diabetic is especially prone to this syndrome. This may be due to the physiologic make-up of the female and their body changes during pregnancy.

Open Access Original Research Article

Assessment of Knowledge and Practice about Mosquito Born Disease among Rural Population of Kancheepuram District, Tamilnadu

V. Pragadeesh Raja, G. Ravivarman, E. Venmathi, M. Salomi

Asian Journal of Medicine and Health, Page 1-7
DOI: 10.9734/ajmah/2019/v14i130092

Background: Mosquito are one of the well known causing many diseases like Malaria, Dengue, Chikungunya, Lymphatic Filariasis, Japanese Encephalitis. They are more prevalent in rural area due to various social factors and lack of knowledge. The objective of this study was to assess knowledge of people and their practices regarding mosquito borne diseases in rural areas of Kancheepuram district, Tamilnadu.

Materials and Methods: A community based cross sectional study was conducted among the residents of Pooncheri, Kancheepuram district of Tamilnadu, between the period of August 2017 to September 2017 among 124 houses selected. After obtaining informed consent from the participants they were interviewed using a pretested semi structured questionnaire regarding their knowledge and practices on mosquito borne diseases.

Results: The study reported that in case of any symptoms suspected to be of mosquito born disease majority of the study population 82.2% reported consulting doctors.  The most preferred mode of prevention of mosquito bite was usage of spray (33.9%) in the breeding place followed by usage of electric repellents (31.4%).

Conclusion: The study indicated that majority of the study population were unaware bout the prevention practices despite knowing about these diseases. Thus, arises the need for effective propagation in the rural area about prevention strategies of mosquito born disease through mass education and social media.

Open Access Original Research Article

Knowledge, Attitude and Utilization of HIV Post-Exposure Prophylaxis among Health Care Workers at HIV Treatment Centers in Port-Harcourt Metropolis

Henry Chika Onuoha, Maduka Omosivie

Asian Journal of Medicine and Health, Page 1-12
DOI: 10.9734/ajmah/2019/v14i130093

Background: Human Immunodeficiency Virus (HIV) is one of the world's top causes of death. New HIV infections emerge every day, leading HIV patients to seek care at health facilities and prompting health care professionals to undertake risky invasive procedures. And notwithstanding the mediation of science, this poses a risk of occupational exposure among health care workers (HCWs), hence the need for the effective use of HIV post-exposure prophylaxis (PEP). The aim of this study was to assess the knowledge, attitude and utilization of PEP among health care workers at HIV treatment centers in Port-Harcourt metropolis.

Methodology: This descriptive cross-sectional study utilized a pre-tested, structured, self-administered questionnaire on a sample of 204 HCWs chosen by multi-stage sampling method. Data were analyzed and presented using descriptive and analytical statistics.

Results: The study revealed that 39.7% of the respondents had good knowledge of HIV PEP and 96.5% had good attitude towards HIV PEP. Additionally, 22.1% had previously encountered possible occupational exposure to HIV, and only 45.5% of them took PEP. This translates to an overall PEP use of 10.1%. Significant associations were observed between knowledge and attitude towards PEP (p=<0.001), source of information and knowledge (p=<0.001), and source of information and attitude (p=0.02). The study also showed that sex, marital status and designation was associated with utilization of PEP (p=0.01; p=0.04; p=0.02).

Conclusion: The study revealed low utilization of PEP despite the level of good and fair knowledge and a generally positive attitude towards PEP. There exists a gap between knowledge and utilization of PEP, hence the need for periodical retraining of HCWs. This should be supplemented by ensuring the consistent availability and accessibility of PEP at treatment centers.