Open Access Original Research Article

Haemoglobin Genotype, ABO and Rhesus Blood Group Distribution in Briggs Family of Abonnema, Rivers State, Nigeria

Christian, Serekara Gideon, Eze, Evelyn Mgbeoma, Briggs, Sotonye Kenneth

Asian Journal of Medicine and Health, Page 1-8
DOI: 10.9734/AJMAH/2018/44902

Aim: The aim of this study was to assess the distribution of haemoglobin genotype, ABO and Rhesus blood groups amongst members of the Briggs family in Akulga Local Government Area of Rivers State.

Study Design: This was a cross-sectional, field-based study carried out in Abonnema, Akuku-Toru Local Government Area in Rivers State. All samples were analyzed at the Haematology Laboratory, Department of Medical Laboratory Science, Rivers State University, Port Harcourt, Nigeria, between June and August, 2018.

Methodology: Haemoglobin genotype was done through electrophoresis using the cellulose acetate method and ABO and Rhesus blood groups using the tube method. Blood samples were collected from a total of 100 members of Briggs family (59 males and 41 females (age 6 to           60 years).

Results: The data collated revealed that the ABO blood group frequencies were O Rhesus D positive 56%; A Rhesus D positive 24%; B Rhesus D positive 17% and  AB Rhesus D positive 3% among members of the Briggs family with no Rhesus D negative subject. HbAA was the commonest haemoglobin genotype, possessed by 80% of the subjects, followed by HbAS with a prevalence of 20%. There was no subject with HbSS.

Conclusion: Greater percentage of members of the Briggs family was of blood group O Rhesus D positive and haemoglobin genotype AA. There was no Rhesus D negative and haemoglobin SS genotype, in the sampled population and considering the fact that Briggs compound or family is like a village in Abonnema, this finding is so unique in that there are social and medical advantages it offers in health (sickle cell disease) and selection of spouses.

Open Access Original Research Article

The Investigation on the Correlation between Obesity Indicator and Hepatitis B and C

Wei-Cheng Shiao, Jau-Nan Lin, Tsan Yang

Asian Journal of Medicine and Health, Page 1-7
DOI: 10.9734/AJMAH/2018/45066

Background: Obesity is an important health issue worldwide, and hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are the two major causes of liver disease that lead to Taiwan's medical health and socio-economic problems. There are currently few studies in the nation on the correlation between obesity indicators and hepatitis B and C.

Purpose: This study uses adult health check data analysis to understand the correlation of obesity indicators and hepatitis B and C.

Methods: This study is a cross-sectional research. The study collected people who did health examinations of a regional hospital in Kaohsiung from 2011 to 2016. The waist circumference (WC), body mass index (BMI), and waist-height ratio (WHR) are used as obesity indicators.

Results: A total of 16,459 cases were included in the analysis. The prevalence of abnormal WC is 20.5%, and the WHR abnormal prevalence rate is 32.1%. Underweight Body Mass Index (BMI) BMI ≤ 18.4 kg/m2 (3.8%), normal BMI ranging from 18.5-23.9 kg/m2 (48.1%), overweight BMI ranging from 24.0-26.9 kg/m2 (26.7%), obesity BMI ≥ 27 kg/m2 (21.4%). The abnormal rate of hepatitis B was 13.6%, and the abnormal rate of hepatitis C was 1.9%. Logistic regression analysis shows that WC is a risk factor for hepatitis B (OR=1.181, 95%CI=1.014-1.377), and WHR is a protective factor (OR=0.771, 95%CI=0.673-0.885). WHR is a risk factor for hepatitis C (OR=1.571, 95%CI=1.246-1.981).

Conclusions: The WC and WHR are respectively the risk factors for hepatitis B and hepatitis C, and the WHR is the protective factor for hepatitis B.

Open Access Original Research Article

Serological and Immunohistochemical Prevalence of Human Cytomegalovirus Co-infection among Hepatitis C Virus Patients Admitted to Kafer El Shiekh Liver and Heart Institute, Egypt

Hany M. Ibrahim, Faten R. Abdel Ghaffar, Rabie E. El Shaer, Mohamed A. Madian

Asian Journal of Medicine and Health, Page 1-10
DOI: 10.9734/AJMAH/2018/45313

Background: Human cytomegaloviruses (CMV) and Hepatitis C virus (HCV) are badly affecting the liver and can lead to hepatitis. Co-infection of CMV and HCV could accelerate the disease pathogenesis and dramatically diminish its treatment.

Aim: The current study is aimed to determine the prevalence of CMV diagnosed serologically and immunohistochemically among the HCV patients and to assess the biochemical and haematological alterations in such co-infection.

Results: Overall prevalence of CMV infection was 47.83%, and 4.00%, using ELISA, and immunohistochemistry. No significant difference was detected in the prevalence of CMV among HCV patients based on gender, residence, age and HCV RNA load. Liver cirrhosis at patient with concomitant CMV IgG and chronic HCV infections showed a high percentage compared to those patients with chronic HCV mono-infection. Moreover, a significant reduction in the level of RBCs count, PCV, and Hb concentration was detected in patients with concomitant CMV and chronic HCV infections compared to patients with chronic HCV mono-infection.

Conclusion: CMV infection is frequent among HCV patients in Egypt. Obtained data recommend that screening and treating for CMV is of great importance among HCV patients in order to lessen the clinical outcome of chronic HCV infection.

Open Access Original Research Article

The Prevalence of Irritable Bowel Syndrome (IBS) in a Private-University in Malaysia, and Its Associated Factors Including Stress, Depression and Anxiety

Ibrahim R. S. AbdelSalam, Meer Ahmad A. M.

Asian Journal of Medicine and Health, Page 1-12
DOI: 10.9734/AJMAH/2018/45604

Background to the Study: Information on the prevalence of Irritable bowel syndrome (IBS) in the Asian population is relatively scanty although it is prevalent in the general population. There have only been few Asian studies concerning anxiety, stress and depression in their association with IBS. IBS is a common gastrointestinal disorder, and its prevalence and demographics have been only been studied using different methodologies and with varying results.

Objectives: To determine the prevalence of IBS among nursing students at MAHSA University, Malaysia, and to determine whether anxiety, depression, stress is associated with IBS, besides determining the common sub-types.

Methods: This cross-sectional study was conducted from March to July 2017 at MAHSA University, Malaysia on nursing students from the Faculty of Nursing. All participants completed a self-administered Questionnaire.

Results: The prevalence of IBS among nursing students according to Rome Ⅲ criteria was 46.8%. The commoner sub-type of IBS was IBS-Diarrhea (44, 46.8%) followed by IBS-Constipation (38, 40.4%) and IBS-Mixed (12, 12.8%). Students who stayed at the hostel had significant association with IBS-C (p < 0.05) compared to IBS-D and IBS-M. Depression and IBS were significantly associated (p < 0.05).

Conclusion: The prevalence of IBS among nursing students studying in MAHSA University, Malaysia is 46.3% which is conspicuously higher than in previous studies in other countries. IBS-D is the commonest sub-type of IBS (46%). In addition, IBS is significantly associated with depression, but anxiety and stress are not. There is no significant association between IBS and Socio-demographic factors, except in gender.

Open Access Original Research Article

User’s Perception and Satisfaction with Services Provided under National Health Insurance Scheme: A Case Study of Academic Staff of Usmanu Danfodiyo University, Sokoto

Nasiru Lawal, M. M. Maishanu, A. A. Aliyu

Asian Journal of Medicine and Health, Page 1-9
DOI: 10.9734/AJMAH/2018/43684

Aim: To assess user’s perception and satisfaction with the National Health Insurance Scheme (NHIS).

Study Design: This descriptive cross-sectional study, conducted between October and December 2017, focused on academic staff who was users of NHIS at the Usmanu Danfodiyo University Sokoto, Sokoto state, Northwest Nigeria.

Methodology: Two hundred and seventy eight academic staff completed a self-administered questionnaire.

Results: Findings revealed that nearly all 276(99.3%) of the respondents were aware of the NHIS but less than half 136(48.9%) enrolled into the scheme. Majority 81(59.6%) of NHIS service users access services at university clinic. About half 148(53%) of the users had poor knowledge of how the scheme works, with 168(60.4%) agreeing that NHIS has provided easy access to healthcare, while 220(79.1%) agreed that it protects families from financial hardship of large medical bills. Out of 136 (48.9%) service users enrolled into the scheme 92(67.6%) were dissatisfied with the process of enrolment while 93(68.4%) were satisfied with the attitude of NHIS staff. With regards to the waiting time at NHIS clinic, 80 (58.8%) were dissatisfied, and in terms of drug administration, 99(72.8%) were dissatisfied with the drugs received at the NHIS pharmacy. Majority 98(72.1%) of the service users rated the overall satisfaction as poor and would not recommend the NHIS services for family members/friends.

Conclusions: Based on the findings, it was concluded that the service users overall satisfaction with service provision was poor. It was therefore recommended that periodic survey of user’s satisfaction and factors influencing it should be carried out by health Institutions, and the findings used as a guide in policy and decision making, towards improving service delivery and users satisfaction.