Open Access Original Research Article

Bacteriology of Suya Meat Sold in Bonny Local Government Area, Rivers State

Konne, Felix Eedee, Monsi, Tombari Pius, Wokem, Gloria Ngozika

Asian Journal of Medicine and Health, Page 1-7
DOI: 10.9734/AJMAH/2018/34160

Background: Suya Meat is made from roasted or smoked beef using the boneless parts of the meat. Suya meat microbial contamination can occur by air, human handlers, equipment, water, papers and utensils.

Aim: This study aimed at determining the level of bacterial contamination of roasted Suya meat sold in Bonny Local Government Area.

Materials and Methods: The sample locations were Tennis Hut, Golf Club, Ama-Hausa, Hospital Road (Junction), Finima market junction and Akiama in Bonny. Five different roasted meat samples were collected at random, from six locations in Bonny. Morphological characteristics of bacteria were noted after 24 hrs incubation period. Identifications of isolates were carried out using standard methods.

Results: The results show that six genera of bacteria which include Bacillus cereus, Salmonella species, Staphylococcus aureus, Klebsiella species, Enterococcus species and Proteus species were isolated. The total number of Bacillus cereus and Salmonella species presence were 10 (34%) and 5 (17%) respectively, from the five Suya samples each, across the six Suya stand in Bonny. Escherichia coli have no growth. The total of 1 (3.4%) and 2 (6.8%) of Staphylococcus aureus and Klebsiella species respectively were also isolated. A total of 6 (20%) and 5 (17%) of Enterococcus species and Proteus species respectively were also isolated. The Tennis Hut and Golf club have a total of 3 (9.6%) and 2 (6.4%) of different types of microorganisms isolated. Finima, and Akiama have 7 (22%) and 6 (19%) respectively of the different kind of microorganisms isolated. Some of these microorganisms are contaminations from the environment while others are regular flora.

Conclusion: The findings show the contamination of the roasted meats with some pathogenic bacteria such as Bacillus cereus, Salmonella species, Staphylococcus aureus, and Klebsiella species.

Open Access Original Research Article

Prognostic Value of NT-proBNP Concentrations in Patients Attending a Hospital Cardiac Service

M. Amrane, K. Abdelkebir, A. Khenchouche, B. Nada, H. Rahmoune, K. Boussouf, A. Bahlouli, I. Oueheb, Z. Zaidi, A. Touabti

Asian Journal of Medicine and Health, Page 1-10
DOI: 10.9734/AJMAH/2018/38288

Objective: Measurement of N-terminal pro-brain natriuretic peptide (NT-proBNP) in the assessment of patients with the acute coronary syndrome has appeared to be a useful prognostic marker of cardiovascular risk. The purpose of this study is to determine if the NTpro-BNP could be a biological marker in evaluating the severity of the disease in patients with the acute coronary syndrome (ACS).

Materials and Methods: This study has included 130 patients attending hospital cardiology department (Sétif Central University Hospital (Algeria)), 47 women and 83 men. All were affected by the coronary syndrome. This study was conducted for 5 months. Several tests were used, ECG, echocardiography, measurement of NT-proBNP, Homocysteine, C-reactive protein (CRP), Vitamin B9 in addition to biochemical and haematological profiles. Data were analysed using SPSS Version 21.0.

Results: The average age of coronary patients was 63.89 ± 12.68 years, with a high predominance of men (63.8%) compared to women (36.2%). There was a significant positive correlation between NT-proBNP and age, homocysteine, Hs-CRP, urea, creatinine, ASAT, ALAT, LDH, γGT, uric acid and fibrinogen. On the other side, NT-proBNP had a negative correlation with sodium, haemoglobin, creatinine clearance and LVEF. The statistical analysis a grouping patients according to NT-proBNP levels. They were separated into two groups (NT-proBNP ≤900 pg/ml, NT-proBNP>900 pg/ml). Then we correlated all parameters (biochemical, haematological, clinical signs) with the different risk factors).

Conclusion: NT-proBNP is a valuable marker for predicting the severity of coronary artery disease in patients with the acute coronary syndrome.

Open Access Original Research Article

First Trimester Fasting Blood Glucose as a Screening Tool for Diabetes Mellitus in a Teaching Hospital Setting in Nigeria

M. Abbey, T. Kasso

Asian Journal of Medicine and Health, Page 1-9
DOI: 10.9734/AJMAH/2018/39385

Aim: The study sought to ascertain the performance of first trimester fasting blood glucose as a screening tool for diabetes mellitus (gestational or pre-gestational), to justify its introduction as one of the booking blood tests in the first trimester and to determine the association of risk factors with gestational diabetes.

Study Design: This is an observational cross-sectional study.

Place and Duration of Study: The study took place at the University of Port Harcourt Teaching Hospital in Rivers State, Nigeria from June 2016 to January 2017.

Methodology: Venous blood was drawn for fasting blood glucose from 288 consented consecutive maternities attending the antenatal clinic in the first trimester. Demographic, obstetric, medical, social and family history was taken from the patients. Data was collected on excel spread sheet, cleaned and then analyzed with SPSS-19 software.

Results: The prevalence of gestational and overt diabetes was 21.2% and 2.4% respectively. There was no statistical significant difference in the prevalence of diabetes among women of various groups except “parity” where the difference was significant – 5.9%, 15.4%, 30.4% and 50.0% in nulliparous, Para 1, multiparas and grand multiparas respectively (P = 0.03). There were however tendencies towards higher prevalence in women of age 40-49 years (42.86%), with secondary education (24%), maternal weight of ≥ 80 Kg (25.5%), BMI ≥ 30 (30%) and previous deliveries of babies ≥ 4.0 Kg (39.1%).

Conclusion: The prevalence of gestational diabetes was 21.2% while overt diabetes 2.4% when women were screened in the first trimester with fasting blood glucose. The findings underscore the urgent need for routinely doing fasting blood glucose for patients in the first trimester.

Open Access Minireview Article

Disconnected Pancreatic Duct Syndrome: A Neglected Entity

Hayfa Alolayan

Asian Journal of Medicine and Health, Page 1-5
DOI: 10.9734/AJMAH/2018/39992

Pancreatic fistula is one of the complications of acute necrotizing pancreatitis (ANP), chronic pancreatitis, trauma, surgery, and malignancy. Disconnected pancreatic duct syndrome (DPDS) is one of the potential complications, however, not as well known. The approach to DPDS is clinically different than the approach to a simple pancreatic fistula, with unique diagnostic and therapeutic challenges to minimize morbidity and facilitate a smooth recovery. The aim of this mini-review is to provide clinicians with the most recent updates regarding early detection and to discuss the changing models for its management and methods for treating appropriate pathways.

Open Access Case Study

Adult-onset Stills Disease: Advocating for New Markers to Overcome the Diagnostic Challenge

Arun Agarwal, Aakanksha Agarwal

Asian Journal of Medicine and Health, Page 1-8
DOI: 10.9734/AJMAH/2018/39960

Adult-onset Still's disease (AOSD), is the adult form of systemic juvenile rheumatoid arthritis (juvenile Still's disease). AOSD is a known cause of fever of unknown origin (FUO). It is characterised by a triad of symptoms: spiking fever (>39°C), salmon-coloured rash and arthritis/arthralgia. However, rash is not easily appreciated in wheatish or dark colour patients as are seen in tropical countries. First described in 1971, it is a rare, difficult to diagnose, idiopathic, autoinflammatory, multisystemic disorder characterised by two subsets according to clinical and laboratory features: systemic or articular. Timely diagnosis and treatment of the disease can prevent complications and lead to a favourable prognosis. We present and discuss a young female patient who presented as FUO and was diagnosed timely as AOSD and treated with corticosteroids and had a desirable outcome and prognosis. We will also discuss the role of some potential biomarkers including procalcitonin and ferritin. Can these markers, along with other biomarkers,  like  IL 18, s100 proteins and sCD163 be included in diagnostic criteria of AOSD need further research, study and meta-analysis?