A Review on the Role of Neuroplasticity in Neurodegenerative Disorders and Its Possible Pharmacological and Non-Pharmacological Interventions
Rana Muhammad Nabeel Aslam
Department of Pharmacy, Government College University Faisalabad, Pakistan.
Noor-ul-Ain
*
Department of Pharmacology, Government College University Faisalabad, Pakistan.
Husnain Ali
Department of Pharmacy, Government College University Faisalabad, Pakistan.
Ayesha Muzammil
Department of Pharmacology, Government College University Faisalabad, Pakistan.
Anam Iqbal
Department of Pharmacology, Government College University Faisalabad, Pakistan.
*Author to whom correspondence should be addressed.
Abstract
Neuroplasticity is the capability of brain cells to interchange as well as modify for the ultimate cause of higher proficiency to acclimatize to the new situations. Neuroplasticity also plays a very pivotal role in the development and then further progressing of neurodegenerative disorders. The severe adjustments in neural plasticity caused by high pressure, anxiety and other terrible stimuli like stress play a considerable role in the onset and cause of depression. This comprehensive review explores the pivotal role of neuroplasticity in neurodegenerative disorders, shedding light on the dynamic adaptive processes of the nervous system in response to pathological conditions. The paper synthesizes current research findings to elucidate the intricate interplay between neuroplasticity and the progression of neurodegenerative diseases. Furthermore, it delves into potential pharmacological and non-pharmacological interventions aimed at modulating neuroplasticity to ameliorate or mitigate the impact of these disorders. By examining diverse strategies, from pharmaceutical interventions to lifestyle modifications, this review contributes to a nuanced understanding of the multifaceted mechanisms underlying neurodegeneration and offers insights into promising avenues for therapeutic development.
Keywords: Neuroplasticity, anxiety, pharmacological, multifaceted, therapeutic