Relationship between Body Mass Index and Low-Density Lipoprotein and Triglycerides in Type 2 Diabetes Mellitus Patients
Nur Nunu Prihantini *
Department of Biochemistry, Faculty of Medicine, Universitas Kristen Indonesia, Indonesia.
Missel Adintia
Department of Biochemistry, Faculty of Medicine, Universitas Kristen Indonesia, Indonesia.
Tranggono Yudo Utomo
Department of Neuroscience, Faculty of Medicine, Universitas Kristen Indonesia, Indonesia and Regional General Hospital, Dr. Chasbullah Abdulmadjid, Bekasi, Indonesia.
*Author to whom correspondence should be addressed.
Abstract
One of the measurements of obesity is using the Body Mass Index (BMI). The increase in obesity is in line with the increase in type 2 diabetes mellitus. Type 2 DM causes disturbances in lipid metabolism in the body, especially hypertriglyceridemia, decreased HDL, and increased small dense LDL. This situation causes patients to have a greater risk of cardiovascular disease. Therefore, researchers want to further investigate the relationship between BMI, LDL, and triglyceride levels. The method used was correlational analysis with a cross-sectional approach using the medical records of Type 2 DM patients at the Indonesian Christian University Hospital for the 2018-2021 period. The study's results obtained a sample of 60 patients with type 2 diabetes mellitus. It was more common in patients of the female sex, ages between 65-74 years, with excess BMI, housewife work, excess LDL levels, and triglyceride levels, which is normal. The correlation test between BMI and LDL was p = 0.588, with a chance ratio of 0.912. Between BMI and triglycerides was p = 0.704 with an odds ratio of 0.702. Spearman rank correlation analysis between BMI and LDL showed a p = 0.895 with r = -0.017. BMI and triglycerides showed a value of p = 0.523 and r = -0.084.
Keywords: Type 2 diabetes mellitus, BMI, triglycerides, low-density lipoprotein