Effects of Botulinum Toxin (BoNT) and Factors on Weight Loss in Normotonic Pylorus (NP) and Hypotonic Pylorus (HP) Patients at Multivariate Level
Ismail Ozsan
*
Department of General Surgery, Okan University, Istanbul, Turkey.
Munevver Turanlı
Istanbul Commerce University, Faculty of Humanities and Social Sciences, Department of Statistics, Sütlüce, Istanbul, Turkey.
Serdal Gunduz
Cyprus Health and Social Sciences University, General secretary, Turkish Republic of Northern Cyprus
Kadir Yılmaz
Istanbul Commerce University, Graduate School of Sciences, Department of Statistics, Istanbul, Turkey.
*Author to whom correspondence should be addressed.
Abstract
Background: In this retrospective research, it was aimed to evaluate effects of botulinum toxin (BoNT) and factors on weight loss in normotonic and hypotonic pylorus patients at multivariate level.
Methods: A total of 671 patients attempted to our clinic between 2020 July to 2022 July were subjected to the study divided by two groups as NP (n=581) and HP (n=90).
Results: Most of patients were female in both groups were females, but male rate in NP group was significantly higher (p<0.05). BMI, weight, weight difference and BMI difference means were significantly higher in NP group (p<0.05). Ursactive rate was significantly higher in HP group (p<0.05). Weight difference was significantly correlated with group (r=-0.267; p<0.01), gender (r=0.161; p<0.01), BMI (r=0.303; p<0.01), BMR (r=0.267; p<0.01), height (r=0.143; p<0.01), weight (r=0.328; p<0.01) and medicine usage (r=-0.082; 0.05). BMI difference was significantly correlated with group (r=-0.262; p<0.01), BMI (r=0.305; p<0.01), BMR (r=0.158; p<0.01) and weight (r=0.239; p<0.01). Generalized Linear Model (Logit Model) results showed that NP (B=3.497; p<0.01), BMI (B=0.342; p<0.01) and BMR (B=0.004; p<0.01) had significant contribution on weight difference.
Conclusion: BoNT is more effective in normotonic pylorus patients than hypotonic pylorus for weight loss and BMI reduction.
Keywords: Botulinum toxin, normotonic, hypotonic pylorus