Demographic Profile, Presenting Complaints and Clinical Findings of Dengue Fever Patients in a Tertiary Care Hospital of Bangladesh
Asian Journal of Medicine and Health,
Background & Objective: Dengue is an important tropical infection caused by an arbovirus having four serotypes (DENV-1, DENV-2, DENV-3, DENV-4) transmitted through the bite of infected female Aedes mosquito. Dengue is a challenging disease with multisystemic, varied, atypical, and sometimes life-threatening presentations. It presents as varied clinical spectrum of dengue fever (DF), dengue hemorrhagic fever (DHF), dengue shock syndrome (DSS) and expanded dengue syndrome (EDS) with atypical presentations, thus posing a diagnostic dilemma. Each year, thousands of dengue infections are reported and there are several outbreaks of dengue in several countries including Bangladesh and this imply the global importance of this infection. The objectives of this study were to determine the sociodemographic variables, presenting complaints and clinical findings of patient suffering from dengue fever during an epidemic outbreak.
Methods: This hospital review analyzed the hospital records of dengue fever cases of BIRDEM General Hospital, Dhaka from June 2019 to December2019. Patients with suspected dengue fever attending at the outdoor/emergency or admitted indoor were taken as case. Data was collected from hospital records. Study protocol was approved by the Institutional Review Board and informed consent was taken from the subjects. All the relevant data regarding history and examination findings of the patients, the laboratory reports were collected. Statistical package for social science (SPSS) version 22, a computer-based software was used for all data entry and statistical analysis.
Results: Total 292 dengue patients were enrolled in this study. Mean age of all patient was 35.63±15.22 years (11-85 year) with male predominance (54.8%). Maximum patients were hailed from urban residence (83.9%), non-smoker (73.6%), had active lifestyle (63.4%) and normal body mass index (68.5%). Overall, 65.1% patients had no comorbidity and 89.4% had no concurrent acute illness.Majority of the patients had high grade fever (76%) for 2-5 days (71%). Bodyache (63.7%), headache (42.1%), vomiting (41.1%), loose motion (16.8%) and abdominal pain (14.7%) were the top five chief complaints along with fever. Most of the patients had normal systolic (86.3%) and diastolic (92.5%) blood pressure.
Conclusion: Although the results of this study cannot be generalized to other cities of Bangladesh, our findings will allow public health agencies in Bangladesh to concentrate their efforts to battle dengue and also suggests that monitoring where Aedes are found will help identify populations at risk". Our study will guide doctors of all level to early diagnose dengue patient and will help them to detect the severe cases early. So that early intervention can decrease the morbidity and mortality.
- dengue fever
- clinical findings
- presenting complain
How to Cite
Reiter P. Weather, vector biology, and arboviral recrudescence. In The arboviruses: Epidemiology and Ecology. CRC press. 2020;245-256.
Moore CG. Predicting Aedes aegypti abundance from climatologic data; 1985.
Arcari P, Tapper N, Pfueller S. Regional variability in relationships between climate and dengue/DHF in Indonesia. Singapore Journal of Tropical Geography. 2007; 28(3):251-72.
WHO, Dengue and severe dengue. 2020.
Accessed March 20, 2020.
Mustafa MS, Rasotgi V, Jain S, Gupta VJ. Discovery of fifth serotype of dengue virus (DENV-5): A new public health dilemma in dengue control. Medical Journal Armed Forces India. 2015;71(1):67-70.
Directorate general of health services. National guideline for clinical management of dengue syndrome. 4th Edition; 2018.
Akram A. Alarming turn of dengue fever in Dhaka city in 2019. Bangladesh Journal of Infectious Diseases. 2019;17;6(1):1-2.
Institute Pasteur. Shedding light on the burden of dengue in Bangladesh. ScienceDaily. ScienceDaily; 2019.
Prattay KM, Sarkar MR, Shafiullah AZ, Islam MS, Raihan SZ, Sharmin N. A retrospective study on the socio-demographic factors and clinical parameters of dengue disease and their effects on the clinical course and recovery of the patients in a tertiary care hospital of Bangladesh. PLoS neglected tropical diseases. 2022;16(4):e0010297.
Amin MM, Hussain AM, Murshed M, Chowdhury IA, Mannan S, Chowdhury SA, Banu D. Searo-Diagnosis of Dengue Infections by Haemagglutination Inhibition Test (HI) in Suspected Cases in Chittagong, Bangladesh; 1999.
Karunakaran A, Ilyas WM, Sheen SF, Jose NK, Nujum ZT. Risk factors of mortality among dengue patients admitted to a tertiary care setting in Kerala, India. Journal of infection and public health. 2014;7(2):114-20.
Sharmin S, Viennet E, Glass K, Harley D. The emergence of dengue in Bangladesh: epidemiology, challenges and future disease risk. Transactions of The Royal Society of Tropical Medicine and Hygiene. 2015;109(10):619-27.
Alam AS, Sadat SA, Swapan Z, Ahmed AU, Karim MN, Paul HK, Zaman S. Clinical profile of dengue fever in children. Bangladesh Journal of Child Health. 2009; 33(2):55-8.
Kabir MR, Rahman N, Iqbal A, Azad F, Tithi SH, Uddin MH, Mostary U, Tanvir M, Tanzim MZ, Mahim MA. Socio-demographic, Environmental and Life Style Factors on the Dengue Epidemic in Noakhali District, Bangladesh: Evidence from Recent Outbreak. Journal of Communicable Diseases (E-ISSN: 2581-351X & P-ISSN: 0019-5138). 2020;52(4):57-65.
García-Rivera EJ, Rigau-Pérez JG. Dengue severity in the elderly in Puerto Rico. RevistaPanamericana de SaludPública. 2003;13(6):362-8.
Kaplan JE, Eliason DA, Moore M, Sather GE, Schonberger LB, Cabrera-Coello LU, DE Castro JF. Epidemiologic investigations of dengue infection in Mexico, 1980. American Journal of Epidemiology. 1983;117(3): 335-43.
Antony J, Celine TM. A descriptive study on dengue fever reported in a Medical College Hospital. Sahel Medical Journal. 2014;17(3):83.
Patil PS, Chandi DH, Damke S, Mahajan S, Ashok R, Basak S. A retrospective study of clinical and laboratory profile of dengue fever in tertiary care Hospital, Wardha, Maharashtra, India. J Pure Appl Microbiol. 2020;14(3):1935-39.
Hasan MJ, Tabassum T, Sharif M, Khan MA, Bipasha AR, Basher A, Islam MR, Amin MR, Gozal D. Clinico-epidemiologic characteristics of the 2019 dengue outbreak in Bangladesh. Transactions of The Royal Society of Tropical Medicine and Hygiene. 2021;115(7): 733-40.
Pamukcu B, Oflaz H, Onur I, Cimen A, Nisanci Y. Effect of cigarette smoking on platelet aggregation. Clinical and Applied Thrombosis/Hemostasis. 2011;17(6):E175-80.
Singer M, Baer H, Long D, Pavlotski A. Introducing medical anthropology: a discipline in action. Rowman & Littlefield; 2019.
Farinelli EC, Baquero OS, Stephan C, Chiaravalloti-Neto F. Low socioeconomic condition and the risk of dengue fever: a direct relationship. Acta tropica. 2018;180:47-57.
Schmidt WP, Suzuki M, DinhThiem V, White RG, Tsuzuki A, Yoshida LM, Yanai H, Haque U, HuuTho L, Anh DD, Ariyoshi K. Population density, water supply, and the risk of dengue fever in Vietnam: cohort study and spatial analysis. Plos Medicine. 2011;8(8):e1001082.
World Health Organization. Comprehensive guideline for prevention and control of dengue and dengue haemorrhagic fever; 2011.
World Health Organization. Global strategy for dengue prevention and control 2012-2020.
Apisarnthanarak A, Mundy LM. Is dengue virus infection an occupational health problem?. Clinical Infectious Diseases. 2009;48(1):135-7.
Rigau-Pérez JG, Clark GG, Gubler DJ, Reiter P, Sanders EJ, Vorndam AV. Dengue and dengue haemorrhagic fever. The Lancet. 1998;352(9132):971-7.
Waggoner JJ, Gresh L, Vargas MJ, Ballesteros G, Tellez Y, Soda KJ, Sahoo MK, Nuñez A, Balmaseda A, Harris E, Pinsky BA. Viremia and clinical presentation in Nicaraguan patients infected with Zika virus, chikungunya virus, and dengue virus. Clinical Infectious Diseases. 2016:ciw589.
Yunus EB, Bangali AM, Mahmood M, Rahman MM, Chowdhury AR, Talukder KR. Dengue Outbreak 2000 in Bangladesh: From Speculation to Reality and Exercises; 2001.
Kalayanarooj S, Vaughn DW, Nimmannitya S, Green S, Suntayakorn S, Kunentrasai N, Viramitrachai W, Ratanachu-Eke S, Kiatpolpoj S, Innis BL, Rothman AL. Early clinical and laboratory indicators of acute dengue illness. Journal of Infectious Diseases. 1997;176(2): 313-21.
Balmaseda A, Hammond SN, Pérez MA, Cuadra R, Solano S, Rocha J, Idiaquez W, Harris E. Assessment of the World Health Organization scheme for classification of dengue severity in Nicaragua. The American journal of tropical medicine and hygiene. 2005;73(6): 1059-62.
Brady OJ, Gething PW, Bhatt S, Messina JP, Brownstein JS, Hoen AG, Moyes CL, Farlow AW, Scott TW, Hay SI. Refining the global spatial limits of dengue virus transmission by evidence-based consensus; 2012.
Peppler RA. Knowing which way the wind blows: Weather observation, belief and practice in Native Oklahoma. The University of Oklahoma; 2011.
The daily star. Dengue situation in Bangladesh takes alarming turn; 2019.
Available at: https://www.thedailystar.net /backpage/ news/dengue-situation-in-bangladesh-takes-alarming-turn-1761832?
Accessed on July 17, 2019
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