Systematic Review of Visceral Leishmaniasis in Central Africa

Demba Kodindo Israël

Ministry of Public Health N’Djaména, Chad.

Cheick Amadou Coulibaly

Leishmaniasis Unit, International Center for Excellence in Research (ICER-Mali), Faculty of Medicine and Odonto-stomatology, University of Science, Techniques and Technologies of Bamako (USTTB), BP 1805, Mali.

John C. Beier

Department of Public Health Sciences, University of Miami Miller School of Medicine Miami, Florida 33136 USA.

Gunter C. Muller

Department of Parasitology, Kuvin Centre for the Study of Infectious and Tropical Diseases. The Hebrew University - Hadassah-Medical School Jerusalem, Israel.

Seydou Doumbia *

Leishmaniasis Unit, International Center for Excellence in Research (ICER-Mali), Faculty of Medicine and Odonto-stomatology, University of Science, Techniques and Technologies of Bamako (USTTB), BP 1805, Mali.

*Author to whom correspondence should be addressed.


Abstract

In underdeveloped countries, infectious diseases remain one of the most important public health challenges. Visceral leishmaniasis, also known as Kala-azar, is a lethal vector-borne parasitic disease with an increasing number of cases. However, it remains one of the most neglected diseases in the world. It is the most severe form of leishmaniasis and is endemic in 75 countries. Around 95% of the patients live in seven countries: Brazil, Ethiopia, India, Kenya, Somalia, South Sudan, and causes about 20,000-40,000 deaths per year of which 50-70% are children. In Central Africa, this pathology is little known and less documented, making it difficult to access information. We have performed this study to characterize the knowledge on the epidemiology of visceral leishmaniasis in Central Africa. We reviewed the literature on visceral leishmaniasis in Central Africa on the number of reported cases, identified parasites, reservoirs and vectors. The documents consulted came from WHO reports, publications of scientific journals, reports of research institutions and abstracts of scientific conferences consulted online on Pubmed and Google Scholar. The information covers the period from the first reporting of cases in each country until December 2020. The review of the situation of visceral leishmaniasis revealed that it is not a significant public health problem in Central Africa. However, a lot of work remains to be done especially surveillance and research in order to present the exact situation of the disease in this part of the continent. This work would include the underreporting of cases inherent to the weaknesses of the surveillance system in these countries, the clarification of the transmission dynamics of human visceral leishmaniasis, canine leishmaniasis, the identity of parasites and vectors.

Keywords: Visceral leishmaniasis, epidemiology, underestimation, Central Africa


How to Cite

Israël, Demba Kodindo, Cheick Amadou Coulibaly, John C. Beier, Gunter C. Muller, and Seydou Doumbia. 2021. “Systematic Review of Visceral Leishmaniasis in Central Africa”. Asian Journal of Medicine and Health 19 (7):8-20. https://doi.org/10.9734/ajmah/2021/v19i730341.

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