Elevated Levels of Lactate Dehydrogenase Predicts Poor Outcomes for Patients with COVID-19: A Review
Dheaa Shamikh Zageer *
Forensic DNA Center for Research and Training, AL-Nahrain University, Baghdad, Iraq.
*Author to whom correspondence should be addressed.
Abstract
In glucose (Glc) metabolism, lactate dehydrogenase (LDH) functions by changing pyruvate into lactate. Lactate dehydrogenase (LDH) release is induced viacell death, suggesting to disease caused by virus or pulmonary deterioration, such as inflammation of the lung triggered by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). A satisfactory evidence exists by binding elevated lactate dehydrogenase (LDH) levels to the development of coronavirus disease 2019 (COVID-19) complications.
Keywords: lactate dehydrogenase, LDH isozymes, COVID-19, mortality.