The Prevalence of Multi-Drug Resistant Organisms and Their Outcomes in an ICU in Mauritius: An Observational Study

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Published Dec 21, 2020
DOI https://doi.org/10.9734/ajmah/2020/v18i1130270
    Page: 71-78

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Dooshanveer Chowbay Nuckchady
Dr. A. G. Jeetoo Hospital, Volcy Pougnet Street, Port Louis, Mauritius.
Samiihah Hafiz Boolaky
Faculty of Medicine and Health Sciences, University of Mauritius, Reduit, Mauritius.

Abstract

Aims: To assess the prevalence of multi-drug resistant organisms (MDRO) in an ICU of Mauritius and determine the relationship between antibiotic resistance and mortality as well as length of stay and duration of antibiotic use.

Study Design: Retrospective case control study.

Place and Duration of Study: This study examined the data of patients who were admitted from 2015 to 2016 at an ICU in Port Louis, Mauritius.

Methodology: 128 patients on whom cultures were ordered were included. Adjustment was performed using multivariate Cox regression and negative binomial regression.

Results: Out of 214 organisms that were isolated, 68% were an MDRO; 78% of Enterobacteriaceae were ESBL, 86% of Acinetobacter spp., 30% of Enterobacteriaceae and 80% of Pseudomonas spp. were carbapenem resistant while 53% of Staphylococcus aureus were MRSA. After adjustment, MDRO were linked to a non-statistically significant 13% increase in mortality (P = .056), a rise in hospital length of stay from 19 days to 29 days (P = .0013) and an escalation in duration of antibiotic use from 11 days to 24 days (P = 1.3E-10).

Conclusion: Infections with MDRO are common in Mauritius and strategies should be put into place to reduce their prevalence.

Keywords:
Multidrug resistant, prevalence, intensive care units, Mauritius, anti-bacterial agents.

Article Details

How to Cite
Nuckchady, D. C., & Boolaky, S. H. (2020). The Prevalence of Multi-Drug Resistant Organisms and Their Outcomes in an ICU in Mauritius: An Observational Study. Asian Journal of Medicine and Health, 18(11), 71-78. https://doi.org/10.9734/ajmah/2020/v18i1130270
Issue
2020 - Volume 18 [Issue 11]
Section
Short Research Article

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