The Impact of Malnutrition on Respiratory Function: A Systematic Review
Alanoud K. Albanna *
Department of Anesthesiology, Al Rayan National Colleges, Al Madinah Al Munawwara, Saudi Arabia.
Amna Abdelrahman Ali Serebal
Anesthesia Department, Al-Rayan National College of Health Sciences and Nursing, PO Box 167, Al Madinah Al Munawarah, 41411, Saudi Arabia.
Narjes Mansour Al Sebaa
Department of Medicine, Al Rayan Colleges, Al Madinah Al Munawwara, Saudi Arabia.
Rawan Talal Gumgumj
Department of Medicine, Al Rayan Colleges, Al Madinah Al Munawwara, Saudi Arabia.
Reema Mohamed Alsaif
Department of Medicine, Al Rayan Colleges, Al Madinah Al Munawwara, Saudi Arabia.
Rouz Mohammed Ahmed
Department of Medicine, Al Rayan Colleges, Al Madinah Al Munawwara, Saudi Arabia.
Jood Khalid Alqudaihi
Department of Respiratory Care, College of Applied Medical Since in Al Jubail, Imam Abdulrahman Bin Faisal University, Saudi Arabia.
*Author to whom correspondence should be addressed.
Abstract
Malnutrition has a significant impact on lung health, directly affecting the respiratory muscle, immune function, and the progression of chronic lung conditions. This review article finds the primary effects of malnutrition on respiratory function, muscle performance, the immune system, the incidence of respiratory infections, and its impact on patients with chronic lung disease. The Developmental Origins of Health and Disease (DOHaD) theory posits that environmental factors, particularly inadequate nutrition during critical early life stages, can have lasting effects on health. People who did not get enough nutrients during pregnancy or right after giving birth are more likely to get chronic obstructive pulmonary disease (COPD) and asthma as adults. Poor ventilation and worse outcomes in COPD, asthma, interstitial lung disease, and idiopathic pulmonary fibrosis can result from the effects of malnutrition on the contractile capacity of the respiratory muscles. This also interferes with the body’s defense, increasing the risk of infection through compromised T-cell activity, reduced antibody production, and deficiencies in essential micronutrients, such as vitamins D, A, and zinc. Acute respiratory infections increase, recovery takes longer, and death rates rise in seriously ill patients due to these changes. In chronic lung diseases, malnutrition weakens muscles and causes them to become inflamed, resulting in decreased exercise, a lower quality of life, and shorter survival. Targeted nutrition, such as supplements and feeding plans, improves clinical outcomes and reduces mortality for children with recurrent infections and adults with advanced COPD. The high rate of malnutrition in respiratory patients emphasizes the need for nutrition care in respiratory treatment.
Keywords: Malnutrition, respiratory function, respiratory infection, respiratory myopathy, COPD, Chronic lung disease, nutritional support