Emerging Technologies in Ovarian Cancer: Advancements in Treatment Strategies

PILLALAMARRI MADHAVI *

Department of Pharmacology, Pulla Reddy Institute of Pharmacy, Domadugu, Sanga Reddy, Telangana 500043, India.

VADDEMANI SNEHALATHA

Department of Pharmacology, Pulla Reddy Institute of Pharmacy, Domadugu, Sanga Reddy, Telangana 500043, India.

PASUMARTI MAHATHI

Department of Pharmacology, Pulla Reddy Institute of Pharmacy, Domadugu, Sanga Reddy, Telangana 500043, India.

MADHURNA THARUN

Department of Pharmacology, Pulla Reddy Institute of Pharmacy, Domadugu, Sanga Reddy, Telangana 500043, India.

PASUPALA DEVAKI

Department of Pharmacology, Pulla Reddy Institute of Pharmacy, Domadugu, Sanga Reddy, Telangana 500043, India.

*Author to whom correspondence should be addressed.


Abstract

In the Western world, ovarian cancer is the most fatal and second most prevalent gynecologic cancer. Ovarian cancer is usually diagnosed in an advanced stage. Ovarian cancer is a dangerous tumor that affects women’s reproductive systems and poses a significant threat to their health. Researching ovarian cancer is tough due to its genetic heterogeneity, complex pathophysiology, restricted availability of human tissue, unique metastatic mechanisms, and unknown genesis. To gain anatomical knowledge of the pathophysiology of ovarian cancer, novel experimental models must be created. The WHO identifies six main types of ovarian cancers, specifically epithelial tumors which are serous, mucinous, endometrioid, clear cell, seromucinous, and Brenner carcinoma.  Although the exact etiological pathways are still undetermined, it is mostly believed that the ovarian surface epithelium is the main site of most ovarian carcinoma. Abdominal discomfort and distension usually appear for a few months in postmenopausal women. Less is known about the potential ovarian cancer risks connected to other gynecological disorders and operations,  including as polycystic ovarian syndrome, pelvic inflammatory disease, and surgery. Environmental and lifestyle variables include exposure to powdered talc and asbestos, as well as smoking cigarettes, are other possible risks. The epidemiology offers indications about the cause, early identification, primary prevention, and treatment approaches.A diverse category of neoplasm ovarian cancer is typically categorized according to their kind and level of differentiation. It is becoming clear that every major histological form of ovarian carcinoma has distinctive genetic abnormalities that deregulate particular signaling pathways in the tumor cells, even if the present clinical therapy of this heterogeneity is mostly ignored.  Furthermore, the molecular etiology of low-grade and high-grade cancers seems to differ significantly within the most prevalent histological categories. Ovarian carcinoma is a worldwide issue that lacks an efficient screening method and is usually discovered at an advanced stage. For newly diagnosed cancer, platinum-based chemotherapy and cytoreductive surgery are the standard treatments. 

Keywords: Ovarian carcinoma, tumor, pathophysiology


How to Cite

MADHAVI, PILLALAMARRI, VADDEMANI SNEHALATHA, PASUMARTI MAHATHI, MADHURNA THARUN, and PASUPALA DEVAKI. 2025. “Emerging Technologies in Ovarian Cancer: Advancements in Treatment Strategies”. Asian Journal of Medicine and Health 23 (4):102-8. https://doi.org/10.9734/ajmah/2025/v23i41210.

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