Epstein-Barr Virus; A Nascent Viral Link with Oral Squamous Cell Carcinoma
Muhammad Wasif Saleem *
Department of Pathology, Ziauddin University, Karachi, Pakistan
Qamar Jamal
Department of Pathology, Ziauddin University, Karachi, Pakistan
Faraz Ahmed Baig
Department of Pathology, Ziauddin University, Karachi, Pakistan
*Author to whom correspondence should be addressed.
Abstract
Oral squamous cell carcinoma (OSCC) is one of the most common malignancy among both sexes worldwide. Incidence rates have been found to be increasing throughout the world from past few decades. Other than known etiologies like alcohol, smoking and tobacco, viral association has been found to be significant in some cases. Recently, a few studies have stressed on the significance on the role of Epstein - Barr virus (EBV) in OSCC as a risk factor. In this review article, we try to merge facts and link of EBV with OSCC on the basis of multiple significant past studies.
Keywords: Epstein-bar virus (EBV), Oral squamous cell carcinoma (OSCC), carcinogenesis, virology