Vitamin D: A Key Factor in Prostate Health

Lana Lekić *

Faculty of Health Studies, University of Sarajevo,Sarajevo, Bosnia and Herzegovina.

Ervin Alibegović

University Clinical Center Tuzla, Tuzla, Bosnia and Herzegovina.

Jasna Rahimić

Mixed Middle school of Chemistry, Tuzla, Bosnia and Herzegovina.

Bojan Pavlović

Faculty of Sport and Physical Education Sarajevo, University of East Sarajevo, Bosnia and Herzegovina.

Ana Pavlović

MF Master Fizikal, Bojan Pavlovic, Karadjordjeva 6, Bosnia and Herzegovina.

Aida Hamzić-Mehmedbašić

Nephrology Clinic, Clinical Centre University of Sarajevo, Bosnia and Herzegovina.

Aldijana Mahmutović Milićević

Faculty of Pharmacy, University of Tuzla, Tuzla, Bosnia and Herzegovina.

Nehra Mosorović

Faculty of Medicine, University of Tuzla, Bosna and Herzegovina.

Emil Mujkić

University Clinical Center Tuzla, Tuzla, Bosnia and Herzegovina.

Asja Šarić

Faculty of Pharmacy, University of Tuzla, Tuzla, Bosnia and Herzegovina.

Dino Alibegović

Faculty of Medicine, University of Tuzla, Tuzla, Bosnia and Herzegovina.

*Author to whom correspondence should be addressed.


This study examines the correlation between vitamin D levels and the severity of symptoms and quality of life in patients with benign prostatic hyperplasia (BPH). A total of 125 participants were categorized based on their prostate symptoms (mild, moderate, and severe) and vitamin D levels (deficient, insufficient, and optimal). Among those with mild symptoms (n=60), 37.93% were vitamin D deficient, 44.11% had insufficient vitamin D, and 54.83% had optimal levels. For moderate symptoms (n=55), 44.82% were deficient, 47.05% had insufficient, and 41.93% had optimal vitamin D levels. In severe cases (n=10), 17.04% were deficient, 8.82% had insufficient, and 3.22% had optimal vitamin D levels. Overall, 23.02% of participants were deficient, 27.02% had insufficient, and 49.6% had optimal vitamin D levels. Quality of life assessments revealed that 56.8% of participants reported a good quality of life, with 46.66% of these being vitamin D deficient, 57.57% insufficient, and 61.29% optimal. An indifferent quality of life was noted by 29.6% of participants, with 28.57% deficient, 27.27% insufficient, and 29.03% optimal vitamin D levels. A very poor quality of life was reported by 13.6% of participants, with 21.42% deficient, 15.15% insufficient, and 9.67% optimal vitamin D levels. These results indicate a potential association between higher vitamin D levels and improved prostate symptoms and quality of life in BPH patients. Further research is needed to establish causality and underlying mechanisms.

Keywords: Vitamin D, benign prostatic hyperplasia, prostate health, quality of life

How to Cite

Lekić, Lana, Ervin Alibegović, Jasna Rahimić, Bojan Pavlović, Ana Pavlović, Aida Hamzić-Mehmedbašić, Aldijana Mahmutović Milićević, Nehra Mosorović, Emil Mujkić, Asja Šarić, and Dino Alibegović. 2024. “Vitamin D: A Key Factor in Prostate Health”. Asian Journal of Medicine and Health 22 (8):1-5.


Download data is not yet available.


Stewart KL, Lephart ED. Overview of BPH: Symptom relief with dietary polyphenols, vitamins and phytochemicals by nutraceutical supplements with implications to the prostate microbiome. International Journal of Molecular Sciences. 2023;24(6):5486.

Swami S, Krishnan AV, Feldman D. Vitamin D metabolism and action in the prostate: Implications for health and disease. Molecular and cellular endocrinology. 2011 Dec 5;347(1-2):61-9.

Kanaan Y, Copeland RL. The link between vitamin D and prostate cancer. Nature Reviews Cancer. 2022;22(8):435-435.

Devlin CM, Simms MS, Maitland NJ. Benign prostatic hyperplasia–what do we know?. BJU international. 2021;127(4):389-399.

Udom GJ. Treatment modalities for the management of benign prostatic hyperplasia: Past, Present and Future Perspectives. EC Emergency Medicine and Critical Care. 2021;5:10-24.

Yeo JK, Park SG, Park MG. Effects of vitamin D supplementation on testosterone, prostate, and lower urinary tract symptoms: A prospective, comparative study. The World Journal of Men's Health. 2023;41(4):874.

Cho A, Chughtai B, Te AE. Benign prostatic hyperplasia and male lower urinary tract symptoms: Epidemiology and risk factors. Current Bladder Dysfunction Reports. 2020;15(2):60-65.

Yuan P, Wang T, Li H, Lan R, Li M, Liu J. Systematic review and meta-analysis of the association between vitamin D status and lower urinary tract symptoms. The Journal of Urology. 2021;205(6):1584-1594.

Kovačević RR, Peličić DN, Vojinović TB. The association between quality of life and the level of vitamin D in benign prostate hyperplasia. Hospital Pharmacology-International Multidisciplinary Journal. 2023;10(2):1292-1300.

Brown D, Gkeka K, Narayan Y, Katsouri A, Tsampoukas G, Buchholz N. Role of vitamin D in common urological conditions: A narrative review of past decade literature. Longhua Chinese Medicine. 2022;5.