Anti-Urolithiasis Activity of Selected Plant Extracts by Titrimetry Method and Aggregation Assay
Siddhartha Lolla
Department of Pharmacology, Pulla Reddy Institute of Pharmacy, Jawaharlal Nehru Technological University, Dundigal, Hyderabad, Telangana-500043, India.
Harika Peddinti
Department of Pharmacology, Pulla Reddy Institute of Pharmacy, Jawaharlal Nehru Technological University, Dundigal, Hyderabad, Telangana-500043, India.
Sravanthi Gojuvaka
Department of Pharmacology, Pulla Reddy Institute of Pharmacy, Jawaharlal Nehru Technological University, Dundigal, Hyderabad, Telangana-500043, India.
Samrin Saba
Department of Pharmacology, Pulla Reddy Institute of Pharmacy, Jawaharlal Nehru Technological University, Dundigal, Hyderabad, Telangana-500043, India.
Uma Devi Dasari
Department of Pharmacology, Pulla Reddy Institute of Pharmacy, Jawaharlal Nehru Technological University, Dundigal, Hyderabad, Telangana-500043, India.
Madhavi Pillalamarri *
Department of Pharmacology, Pulla Reddy Institute of Pharmacy, Jawaharlal Nehru Technological University, Dundigal, Hyderabad, Telangana-500043, India.
*Author to whom correspondence should be addressed.
Abstract
A major global health concern with a high recurrence rate is urolithiasis. Various in vivo and in vitro techniques have been effective in assessing the anti urolithiatic capacity of therapeutic plants. Renal stone production can be studied using in vitro models, whereas the pathological implications of urolithiasis are declared using in vivo models. Therefore, preventative management can be considerably and successfully evaluated using in vitro models, whereas urolithiasis treatment can be directed by using in vivo models. This study explains the benefits, drawbacks, and uses of both models, with a focus on the contribution of in vitro research to the assessment of preventive care. We done Physicochemical Tests for Phyllanthus acidus (fruits) Tinospora cordifolia (leaves) and Psidium gujava (fruits and leaves ) and also Preliminary Phytochemical Investigation of Phyllanthus acidus (fruits), Tinospora cordifolia (leaves) and Psidium gujava (fruits and leaves).
Keywords: Kidney stones, aggregation, cystone, spectroscopy, calcium oxalate crystals